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All about D Ribose

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Have You Ever Wondered What is D-Ribose?

Ribose is a sugar molecule that occurs naturally in the body and is made from blood glucose. 1 It is a key component of adenosine triphosphate (ATP) which is the fuel source of every living cell. Involved in storing and releasing energy, muscle contraction, and nerve function it is a really big deal for us. It is even part of our RNA (ribonucleic acid), a molecule involved in protein synthesis and other cell activities. Also known as D-ribose, it is sold as a nutritional supplement for many of its great benefits with 2 popular uses to reduce muscle fatigue and improve energy levels and or athletic performance.

So What Are Some Other Health Benefits of D-Ribose

Fibromyalgia and Chronic Fatigue

D-ribose shows promise in the treatment of symptoms for fibromyalgia and chronic fatigue syndrome (CFS). A 2017 review of dietary modifications for chronic fatigue patients reported that D-ribose supplementation significantly improved energy levels and overall mood.

In a pilot study published in the Journal of Alternative and Complementary Medicine, 41 patients with fibromyalgia and/or chronic fatigue syndrome who were given ribose supplements, 66 percent of the patients showed significant improvement in symptoms such as lack of energy, difficulty sleeping, and pain.

Both fibromyalgia and chronic fatigue syndrome are recognized by impaired energy metabolism. The study's authors suggest that ribose may help treat the two conditions by increasing the production of energy in the heart and muscles where it is needed most

Heart Failure Recovery

Ribose supplements may be of some benefit to heart failure patients. In a 2015 study, Ohio State University researchers gave a small sample of congestive heart failure (CHF) patients 5 grams of D-ribose daily for six weeks. Measurements of heart function improved in 64 percent of subjects, and those improvements were sustained in follow-up assessments three weeks after ceasing supplementation.

Earlier research published in the European Journal of Heart Failure found D-ribose supplements enhanced the quality of life and improved certain measures of cardiac function in CHF patients. In the study, 15 patients were given either D-ribose or a placebo daily for three weeks, then after a one-week break patients were switched over to the alternate treatment for another three weeks.

Fibromyalgia can be a very difficult Problem with many difficult symptoms

D-Ribose benefits for Fibromyalgia

Although we still need more research on d-ribose supplementation for either fibromyalgia or chronic fatigue syndrome there are many healthcare providers recommending its use, Also, there are many testimonials from users of the product expressing how successful d ribose has been and that it is an effective part of dealing with their symptoms. 2 


One small study published in The Journal of Alternative and Complementary Medicine concluded that d-ribose supplementation significantly improved symptoms of these conditions, including:

  • Increasing energy levels 
  • Improving sleep quality 
  • Improving mental clarity 
  • Lowering pain intensity
  • Improving overall well being

A common question for people interested in D Ribose is, How much d ribose should i take and when do i take it?

There is no standard recommended dosage of D-ribose. Based on scientific studies, alternative health practitioners recommend between 5 grams and 30 grams a day to support chronic health conditions. As a workout enhancer, 5 grams a day is the common dose.3

Can you take d ribose at night?

Most "energy drinks" are largely sugar and caffeine and act like energy loan sharks while causing insomnia. Ribose is an energy superstar, and this special sugar was shown to increase energy an average of 61% in a recent study, while also improving sleep and brain function.

How long does it take for d-ribose to start working?

The study found that after three days of supplementing, ATP was recovered to normal levels in the D-ribose group, but not in those taking the placebo. 4

How is d-ribose made?

Cells produce D-ribose through the pentose phosphate pathway (PPP) that is essential for ATP production. In many diseases or conditions, ATP synthesis is reduced, thus supplementation with D-ribose may provide a solution to impaired cellular bioenergetics 5

How to take d ribose

If you're taking it for an exercise boost, a common recommendation is to take it with morning and evening meals or right before and right after physical activity

What is d ribose good for?

  • May Help Recovery of Energy Stores in Your Cells.
  • May Improve Heart Function in People With Heart Disease
  • May Improve Symptoms of Certain Pain Disorders
  • May Benefit Exercise Performance.
  • May Improve Muscle Function.
  • May Help Recovery of Energy Stores in Your Cells.
  • May Improve Heart Function in People With Heart Disease
  • May Improve Symptoms of Certain Pain Disorders
  • May Benefit Exercise Performance.
  • May Improve Muscle Function.

REFERENCES

  1. https://www.drlamcoaching.com/blog/benefits-d-ribose-side-effects-healthy-aging/
  2. https://www.webmd.com/vitamins-and-supplements/ribose-uses-and-risks#:~:text=Some%20research%20suggests%20that%20ribose,heart%20attack%20or%20angina%20episode.
  3. https://draxe.com/nutrition/ribose/
  4. https://www.healthline.com/nutrition/d-ribose#TOC_TITLE_HDR_2
  5. https://www.healthline.com/nutrition/d-ribose#TOC_TITLE_HDR_2


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