Skip to content

What Are the Side Effects of Taking Reishi Mushroom Supplements?


What Are the Side Effects of Taking Reishi Mushroom Supplements?

Reishi Mushroom (Ganoderma lucidum) is a staple of traditional Eastern medicine. In recent years it has become extremely popular as a natural supplement which provides a variety of benefits and is a very popular health choice for many Americans.

This mushroom is believed to be a powerful remedy by its name in Chinese, ​ling zhi​, which translates to "herb of spiritual potency," according to PeaceHealth. Reishi Mushroom is included in supplements, extracts, tea blends and even in coffee products. But you'll want to talk to your doctor before taking any Reishi Mushroom — especially if you're on medications

Reishi Mushroom Tea Benefits

While Reishi is linked to better immunity, gut health, cancer therapy and lower blood pressure, it's unclear how these findings would translate to Reishi Mushroom tea. More research is needed to fully understand the purported benefits of Reishi tea.

Side Effects of Reishi Mushrooms

Taking too much Reishi Mushroom may cause adverse effects such as the following, per MSKCC:

Reishi Mushroom's side effects may include nausea and insomnia in some people with cancer. In rare cases, liver toxicity was a reported side effect.

Chronic diarrhea in a man with non-Hodgkin's lymphoma following long-term use of a powdered Reishi Mushroom extract also occurred.

Liver damage is the harshest side-effect when consumed for extended periods, usually over a year, though this risk is incredibly low. The mushrooms may interact negatively with prescription medication or other supplements you may be taking.

People Who Should Avoid Reishi

According to MSKCC, the following groups of people should avoid reishi or talk to their doctors before taking it.

  • Those on blood thinners:​ Do not take reishi if you are currently taking blood thinners including warfarin, as it may increase bleeding.
  • Those on immunosuppressants:​ Reishi can enhance immune response and might make your meds less effective
  • ​Those undergoing chemotherapy:​ It's theorized that reishi might make chemotherapy drugs less effective.
  • ​Those on substrate drugs:​ If you are taking cytochrome P450 2E1, 1A2, and 3A substrate drugs, do not take reishi as lab studies suggest compounds in reishi may affect drug concentrations.
  • ​Pregnant people:​ Talk to your doc before taking any Reishi Mushroom supplements.


If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.

  • Reishi has moderate interactions with at least 73 different drugs.
  • Reishi has mild interactions with at least 78 different drugs.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Check with your physician if you have health questions or concerns.


As with any other supplement, there are always possible risks with taking them especially if you are on medications. But in the case of Reishi Mushroom Supplements, the benefits outweigh the risks. Of course it would be best to air on the side of caution and always seek the guidance of our medical professional as you take the step to improving your health.

We have scanned the market and found that the best Reishi Mushroom Supplements available now are the following

  • BoostCeuticals Reishi Mushroom 450mg
  • Host Defense Mushrooms Reishi
  • Real Mushrooms Reishi




Have any questions or thoughts? Please, feel free to ask away as you share and tag us in your post! BoostCeuticals strive to provide a community who are excited about finding the best boost  they need and living the best life possible, both optimally healthy & happy! 

Your Participation is the energy behind us helping you in your daily healthy boost!

3 Tips On Best Immune Health and Aging In The Coronavirus Environment

As the number of people infected with the coronavirus keeps increasing daily and millions are locked in their homes, Covid-19 is indeed one of the greatest concerns.

Must Reads

Aug 23  2019

Nov 11  2019

Older Post
Newer Post

Leave a comment

Please note, comments must be approved before they are published. No Spam allowed.

Shopping Cart

Your cart is currently empty

Shop now